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1d ago
An RNA molecule contributes to therapy resistance of triple negative breast cancer
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Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer. Chemotherapy before or after surgery remains the standard treatment regimen for stage I–III TNBC. Only a small portion of patients can benefit from targeted therapy with PARP inhibitors because of BRCA mutations. However, resistance to chemotherapy or targeted therapy remains a major hurdle.
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