🔬 Science Apr 25, 2026 · Ben Sullivan

New Microscopy Technique Maps Nine Proteins Inside a Single Nucleus at Once

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Nine proteins. One nucleus. Four hours.
That’s the thumbnail version of what a team at the Indian Institute of Science in Bangalore has pulled off, and it perhaps undersells the achievement a little. Until recently, the best super-resolution microscopes could track only two or three molecular species at once inside a living cell; what the IISc team has done, essentially, is turn a spotlight into a switchboard. Their modified version of a technique called DNA-PAINT can now illuminate nine d

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