Health

Ionis Pharmaceuticals lost more than $1 billion in market value on Monday after the company slashed sales projections for a triglyceride-lowering drug the biotech and Wall Street analysts believe is a potential blockbuster.  The firm announced that it expects the drug, Tryngolza, to bring in $50 million in sales by the end of this year, compared to Ionis’ previous forecast of $100 to $110 million. Third quarter sales came in at $9 million, well below Wall Street consensus expectat

(MedPage Today) -- Women exposed to doxycycline in early pregnancy had an increased risk of pregnancy loss compared to other antibiotics, a cohort study showed. Doxycycline use for respiratory tract infection was linked with increased pregnancy...

(MedPage Today) -- The enthusiasm for smartwatch detection of left ventricular systolic dysfunction (LVSD) was tempered by a Korean study indicating difficulties with the technology in its current state. Using an artificial intelligence (AI)-ECG...

(MedPage Today) -- Police in California are investigating after at least two dozen participants in the Santa Barbara Half Marathon ended up at the hospital on Sunday. The Santa Barbara Police Department said in a statement it opened an investigation...

Brandi Deason, BSN, RN, works in the Neonatal Intensive Care unit at Monroe Carell Jr. Children’s Hospital at Vanderbilt. She is one of the latest Vanderbilt Health DAISY Award winners.  From the nomination “There are nurses who care for patients, and then there are nurses who change a family forever. Brandi Deason is one of those rare nurses. Our son was a tiny warrior who fought in the NICU. During that time, Brandi didn’t just care for him, she truly knew him; his personality

(MedPage Today) -- In patients treated with resmetirom (Rezdiffra), early responses in blood and imaging biomarkers were associated with resolution of metabolic dysfunction-associated steatohepatitis (MASH) and fibrosis improvement, according to...

The Food and Drug Administration on Monday approved Bayer’s drug to reduce recurrence of stroke, making available the first in a novel class of medications that hold the promise of preventing blood clots more safely. Many blood thinners aren’t used in this setting due to the increased risk of bleeding. But Bayer’s drug, which will be sold under the brand name Sunharbo, inhibits a protein called XIa, utilizing a mechanism that’s thought to stop the formation of bad

Chloe Kight, BSN, RN, works in the Pediatric Cardiac Intensive Care unit at Monroe Carell Jr. Children’s Hospital at Vanderbilt. She is one of the latest Vanderbilt Health DAISY Award winners.  From the nomination “Chloe has been a nurse and leader in the PCICU for nine years and is very dedicated to the PCICU and the education of our staff.  She is always willing to jump in and help whether she is in the office or out in the unit. She is very kind and approachable, making staff

(MedPage Today) -- A public spat between former Trump administration officials over alleged corruption in public health policymaking is the latest front in Republicans' postelection recriminations, a battle that has exposed fault lines within the...

(MedPage Today) -- About one in four U.S. adults endorsed childhood vaccinations or acetaminophen (Tylenol) use during pregnancy as an autism risk factor, a cross-sectional study showed. In a nationwide survey of 30,000 adults, 26.6% endorsed...

(MedPage Today) -- ML-007C-MA, an investigational muscarinic M1/M4 receptor agonist that combines betovumeline and fesoterodine fumarate, significantly improved schizophrenia symptoms in adults who had an acute exacerbation of psychosis, data from...

A long-running teen driver safety program at Monroe Carell Jr. Children’s Hospital at Vanderbilt, Be In The Zone (BITZ), shows students that distracted driving is dangerous and potentially deadly. Research has found that dialing a phone number while driving increases a teen’s risk of crashing by six times, and texting while driving increases the risk by 23 times. The Trauma Injury Prevention Program at Monroe Carell is a nationally recognized program with a focus on reducing traumatic inju

A new stem-cell model that recreates the first stages of human placenta development provides a powerful platform for studying how pregnancy begins and fails.

After months of skirmishing, the Trump administration removed WuXi AppTec, a key contract developer and manufacturer for the pharmaceutical industry, from its list of “Chinese military companies” operating in the U.S. The Department of Defense took this step to comply with a court ruling last August, according to a notice with the Federal Register. At the time, a U.S. District Court judge temporarily blocked the administration from pursuing the designation after WuXi filed a law

(MedPage Today) -- Left bundle branch pacing (LBBP) drastically reduced clinical events among patients with atrioventricular (AV) block, with results good enough to stop the OptimPacing trial early. In that international randomized trial of patients...

(MedPage Today) -- ORLANDO -- Interim results from a prospective trial designed to evaluate safety of avacopan (Tavneos), the embattled drug for antineutrophil cytoplasmic antibody-associated vasculitis (AAV), indicated that the product could...

(MedPage Today) -- Starting valbenazine (Ingrezza) to treat tardive dyskinesia might reduce antipsychotic discontinuation in patients newly diagnosed with the side effect, a retrospective cohort study of Medicare claims indicated. Among patients...

(MedPage Today) -- Two large trials conducted in Brazil in different patient populations came to somewhat divergent conclusions on the cardiovascular benefits of intensive blood pressure (BP) lowering. Over roughly 4 years of median follow-up...

NEW YORK — If you’re blind, Bill Ackman wants to help you see again. That is the ambitious plan the billionaire is pursuing with the Ackman Oxman Institute, a new institution in New York City that will act as a hub for brain injury research, including brain-computer interfaces that can help people move, speak, and connect to digital devices through brain activity.  It’s a new dream with a tragic backstory.Continue to STAT+ to read the full story…

(MedPage Today) -- ORLANDO -- Patients with systemic lupus erythematosus (SLE) that is uncontrolled despite standard therapy did well with a daily oral dose of sirolimus in a trial from China, although safety concerns weren't entirely relieved...