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Declining hippocampal connectivity may predict worsening symptoms in young people at risk for psychosis

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Declining hippocampal connectivity may predict worsening symptoms in young people at risk for psychosis
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One of the central problems in psychiatry is the lack of objective biomarkers: While other areas of medicine have reliable methods for diagnosis and treatment, like X-rays or blood tests, psychiatrists and researchers rely on the patient's self-reported symptoms. In a new study, researchers identified connectivity within the hippocampus as a novel biomarker candidate for the early risk stages of psychotic disorders—and a potential predictor for difficult-to-treat negative symptoms.

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