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Immune system protein is a cancer killer on its own, new study shows

Medical Xpress
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Immune system protein is a cancer killer on its own, new study shows
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For decades, scientists have known that a protein made by T cells and natural killer (NK) cells in the immune system, called perforin, can kill tumor cells by punching a hole in the cell wall and injecting proteases called granzymes, which kill the cell. Now, new work led by researchers at the University of Michigan Health Rogel Cancer Center found that tumor cells could be killed even when major granzymes were missing.

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