💻 Technology 1d ago · John Timmer

Researchers use AI to design proteins that cut up other proteins

Ars Technica
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Researchers use AI to design proteins that cut up other proteins
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A protein is a chain of amino acids held together by what are called peptide bonds. On their own, those bonds are extremely stable; they're estimated to have a half-life of several hundred years. But in Earth's environment, most proteins don't last nearly that long. That's because organisms have evolved a handful of ways to catalyze the break-up of peptide bonds, which have diversified into countless specialized protein-digesting enzymes. Proteases are everywhere and generally make short work of

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