Cancer’s Rogue DNA Has an Achilles’ Heel – and Scientists Just Found It
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Researchers found that blocking a key DNA repair protein destabilizes rogue DNA circles that help drive aggressive cancers, exposing a potential weakness in tumors that rely on ecDNA. Some aggressive cancers carry extra copies of cancer-driving genes on circles of DNA that float outside the cell’s normal chromosomes. These rogue DNA circles can help tumors [...]
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