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Finding a tumor's soft spot to power-up immunotherapy
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Researchers at the USC Viterbi School of Engineering and Keck School of Medicine of USC have engineered a genetic tool that addresses one of the most persistent obstacles in cancer immunotherapy: the physical softness of tumors. The work, detailed in the journal Nature Biomedical Engineering, reveals how the soft environment of a tumor enables cancer cells to become "stealthy" and resistant to treatment, providing a mechanism to tag those evasive cells for destruction.
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