🔬 Science Jun 25, 2026 · Ben Sullivan

Cells Sculpt Themselves Using Swarms of Self-Propelled Actin Bundles

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A glioma cell sitting on a glass dish has no instructions. Nothing outside it is telling it which way to go, where to bulge, where to flatten. And yet, watched under the right microscope, it gets on with the business of moving anyway: a broad sheet of membrane swells out at one edge, the cell tips forward, and off it crawls. For decades that has been one of the maddening puzzles of cell biology. We know cells reshape themselves in response to chemical signals from their surroundings. What we hav

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