🔬 Science 6h ago · Ben Sullivan

Caltech’s Simple, Two-LED Solution Keeps Microscopes Focused Automatically

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Haowen Zhou wasn’t looking for a breakthrough. He was debugging. Somewhere in the code for an unrelated project, something wasn’t adding up, and he and his colleague Shi “Josh” Zhao were methodically working through the numbers when they noticed something odd in the images. When they combined photographs taken from two slightly different illumination angles, a pattern of stripes appeared in the data. Faint, but unmistakeable. And stranger still, the stripes changed depend

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