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For 30 years, doctors chased the wrong immune culprit behind this rare inflammatory disease
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Researchers at the Garvan Institute of Medical Research have uncovered a critical mechanism driving inflammation in mevalonate kinase deficiency (MKD), a rare but devastating autoinflammatory disorder. The study, published in Immunity, reveals that immune cells called natural killer (NK) cells are impaired in MKD, leading to an excessive inflammatory response when patients encounter infections.
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